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Very long-term animal experiments have not been done to assess the carcinogenic prospective of phenylephrine, nor are there other animal or human details relating to mutagenicity.

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Promethazine hydrochloride and phenylephrine hydrochloride syrup is indicated to the non permanent aid of upper respiratory signs, including nasal congestion, linked to allergy or the popular cold.

Geriatric Use Scientific scientific studies of promethazine hydrochloride and phenylephrine hydrochloride syrup didn't include things like sufficient quantities of subjects aged sixty five and more than to ascertain whether they react in a different way from young subjects. Other reported medical encounter hasn't discovered variances in responses between the elderly and youthful patients.

In pediatric sufferers that are acutely ill affiliated with dehydration, There may be an elevated susceptibility to dystonias with using promethazine HCl.

Because recurrences of NMS happen to be reported with phenothiazines, the reintroduction of promethazine HCl needs to be cautiously thought of.

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Phenylephrine with bronchodilator sympathomimetic brokers and with epinephrine or other sympathomimetics.

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Data for Sufferers Promethazine and phenylephrine could trigger marked drowsiness or might impair the psychological and/or Bodily capabilities needed for the performance of probably dangerous tasks, which include driving a car or truck or working equipment.

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Guys with symptomatic, benign prostatic hypertrophy can working experience urinary retention when offered oral nasal decongestants.

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